The University of Colorado Cancer Center has awarded more than $1M in grant funding to 13 researchers on the Anschutz Medical Campus. The funding comes from two programs: Paul Calabresi Clinical Oncology Research Awards (K12) and American Cancer Society Institutional Research Grant (ACS IRG).  Madeleine Kane, MD, PhD, professor of medicine, Division of Medical Oncology, is the PI on both, and Andrew Thorburn, PhD, chair of the department of pharmacology and CU Cancer Center Deputy Director , is the co-PI for the K12.

The rationale behind the K12 award is to produce dedicated and human-oriented oncology research investigators who can independently design, implement and manage all phases of hypothesis-based cancer clinical therapeutic research. The end products of this program are translational oncology researchers who can work effectively in collaborative team research settings to develop cancer clinical trials, obtain independent research funding, publish results in peer-reviewed journals, and mentor junior colleagues.

The American Cancer Society receives approximately 2,000 requests for support of cancer research and for training of health care professionals. All proposals are subjected to multiple levels of rigorous and independent peer review to identify the most meritorious projects for funding.  The ACS IRG is a block grant awarded to an institution to make seed grant cancer research awards to junior faculty pursuing cancer research who have not yet received major grant funding using a rigorous peer-review process. ACS IRG looks for new recipients annually.

Congratulations to the 13 recipients of the grants.

K12 recipients each received $150,000 per annum

Katja Kiseljak-Vassiliades, DO, instructor, University of Colorado School of Medicine, Department of Medicine, Division of Endocrinology, Diabetes and Metabolism 

Robert C. Doebele, MD, PhD, assistant professor, University of Colorado School of Medicine, Division of Medical Oncology

Margaret E. Macy, MD, assistant professor, University of Colorado School of Medicine, Department of Pediatrics

Carrye R. Cost, MD, assistant professor, University of Colorado School of Medicine, Department of Pediatrics

Sana Karam, MD, PhD, assistant professor, University of Colorado School of Medicine, Department of Radiation Oncology

Elaine Lam, MD, assistant professor, University of Colorado School of Medicine, Division of Medical Oncology

American Cancer Society Institutional Research Grant recipients

Diana M Cittelly, PhD, assistant professor, University of Colorado School of Medicine, Pathology   

$30,000 for “Hormonal regulation of the brain microenvironment and its contribution to brain metastatic progression”

Sana Karam, MD, PhD, assistant professor, University of Colorado School of Medicine, Radiation Oncology

$10,000 for “Targeting the EphB1 Gene to Improve Radiosensitization of Head and Neck Cancers”

Katja Kiseljak-Vassiliades, DO, instructor, University of Colorado School of Medicine, Endocrinology

$30,000 for “Molecular Mechanism Underlying Growth Hormone Pituitary Tumors Subtypes”

Alisa B Lee Sherick, MD, instructor, University of Colorado School of Medicine, Pediatrics

$30,000 for “Overcoming Mer receptor tyrosine kinase inhibition resistance mechanisms”

Michael J Morgan, PhD, assistant professor, University of Colorado School of Medicine, Pharmacology

$10,000 for “Targeting Autophagy Dependence in Cancer”

Xiaojun Ren, PhD, assistant professor, University of Colorado School of Medicine, Department of Chemistry.

$10,000 for “Polycomb group protein Cbx2 controls chromosome stability by coordinating with chromosome segregation proteins”

Tamara Terzian, PhD, assistant professor, University of Colorado School of Medicine, Dermatology

$30,000 for “The role of mutant p53 in tumorigenesis”